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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Employment growth exceeded projections.
Paramore, 'After Laughter'

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 跨国化工巨头如何投资中国市场?
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

3. Poverty
10. Deepika Padukone - $10 million

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

n. 保护,防卫

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 家居建材行业路在何方
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Variety Talk Series: “Last Week Tonight With John Oliver” (HBO)

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Everything Else
INDOORS: The two-story stucco contemporary was built in 2005. The interior is an airy open space; white walls contrast with red tile floors. Walls of sliding glass doors face live oaks and marshland on the Wilmington River.
扎克伯格还协助成立了一个名为FWD.us的游说团体,旨在推动美国的移民和教育改革。
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 切实将“套路贷”关进法律笼子
Perspective

Trends and targets in antiviral phototherapy

It also has a lot of inexpensive museums, cheap vintage trams and beautiful pebbly beaches. Day trips to vineyards are easy to arrange.
9. 安布罗斯·阿钦摩西尔(Ambrose Akinmusire),《想像中的救世主更容易描绘》(the imagined savior is far easier to paint),Blue Note。小号手安布罗斯·阿钦摩西尔为自己在Blue Note公司发行的第二张专辑注入了类型不固定,富于探索精神的今日之声,有许多歌手和一支弦乐四重奏组合参与。和这张专辑刚发行的时候相比,如今的他有了更多评论社会的迫切与讥讽时局的精神。
Investigators have arrested one youth and one 18-year-old in connection to the July 9th shooting death, which occurred inside a Jamestown Cres. home.
So what does 2015 portend? Here are some educated guesses.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

adj. 准确的,精确的

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 北京共有产权住房建设进展顺利
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

怎么玩吉他

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

quality
Pushing ahead with the five priority tasks through reform

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 看不动产证 还要看查册表
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

An oversight model drawing on random inspections by randomly selected law enforcement officers or inspectors and requiring the prompt release of results
A historically jittery commodity, crude oil has seen calm prices for three years, and one big factor has been helping smooth the wrinkles: U.S. shale oil.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Best chances: It's always hard to bet against Streep getting a best actress nomination, and Hanks is overdue for an acting nomination after missing out in recent years.
4. 蕾哈娜

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Arlie Russell Hochschild, the author of “Strangers in Their Own Land: Anger and Mourning on the American Right,” describes a feeling of lost opportunity as the “deep story” of the rural Louisiana communities she spent four years studying.
Warm hearted wishes for a happy New Year filled with all your favorite things.
['breik.θru:]
France, along with Belgium, has seen the largest numbers of volunteers leaving to join the Islamic State jihadist group, which has seized large parts of Syriaand Iraq.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Salary three years after graduation and salary increase are the main criteria, each accounting for 20 per cent of the ranking’s weight. Most schools in the top 25 score well on at least one of these criteria. The top 10 schools would mostly also rank in the first 10 if salaries and their increases were excluded. The only exceptions are Nanyang Business School and China Europe International Business School, both underperforming in the doctoral and research ranks.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Some of my work has been set inAmerica, so I am very pleased and honored that my work is loved here.
The charges of Russian hacking and Mr Trump’s evident defects of experience, judgment and character show that the college has not proved the bulwark Mr Hamilton hoped for.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

temporary

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

而在进口一侧,不论以人民币还是美元计,情况都愈发糟糕。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

你感到抓狂是对的。公司无时无刻不在监视着你。无论你做什么都有记录:你打的每个电话,发的每条短信,每条在推特上发的帖子和讯息。在大部分公司,这些记录可永远不会删除(这吓人的吧,真可怕~)
n. 冰箱
[k?n'denst]
2010年英文新年祝福邮件

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

读:口齿-教练要求口齿伶俐。
The state-sponsored purchasing managers' index fell from 50.8 in October to 50.3 in November, the lowest reading since March. Any level above 50 indicates expansion.
读:口齿-教练要求口齿伶俐。
In the past five years, China's exports of goods grew at an annual average of 6.5 percent, with its share in the global market rising form 10.4 percent in 2010 to about 13.2 percent in 2015, faring much better than major global economies. Service trade grew over 13.6 percent each year, marking the world's second largest service trader.
Halloween is just a few days away. Which means, if you haven’t gotten your costume or decorations sorted out yet, you might want to start doing that pretty soon.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

It is the continual shrinkage of components that have unleashed the explosion of computing power and enabled these gadgets to be accessible to people across the world.
据Birinyi Associates的数据,今年迄今为止,各家公司已经宣布了376项股票回购计划,总额高达2,610亿美元。这个数字与2012年相比增长了近72%,但与回购创下纪录的2013年相比,略微有所回落。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The gorgeous Birman cat has more than 128,000 Instagram followers. And it has been the inspiration for many of Lagerfeld's designs.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

New York City, now ranked seventh, has gone up 15 places since last year. It has seen a big jump in costs over recent years, moving up 42 spots since 2011.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

让温馨的祝愿、幸福的思念和友好的祝福,在新年来到你身边,伴你左右。
他们在培养核心球员,寻求合适的角色球员。他们可是湖人队啊,对他们而言,很有可能会有一到两个有实力的自由球员主动投怀送抱。
2.German: 22.2 percent increase
Will Theresa May remain prime minister in 2018

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

印度尼西亚佩母德兰——在巴厘岛的佩母德兰,可以在长了珊瑚的佛像周围进行水肺潜水,也可以到地面上享受海滩胜地和餐馆美食。
罗杰斯对于中间剧情的反转十分不满,因此在拍完前三季之后决定离开剧组。这样的违约行为使他面临数百万美元的诉讼。但讽刺的是,韦恩·罗杰斯从来没有正式和剧组签订过合同(他涉及道德条款方面的问题)。因此该诉讼请求被驳回。你可能会说在这次的事件中,罗杰斯是笑到最后的人,但自从他离开剧组,《风流医生俏护士》又播出了八季,而罗杰斯在他的演艺生涯中再也没有取得过这样的成就。所以说他是笑到最后的人,也许只是一个相对的说法。
The clothes had resonance because the characters who wore them were intricate and multidimensional, not just because Joan’s brocade sheath was really glamorous, or Megan’s psychedelic chiffons made Pucci feel cool.
达奇斯说:年底iphone5和迷你ipad的发布,消除了海内外制造业和乔布斯死后遗留影响的争议,这使得苹果成为年度最大的赢家。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

On the a monthly basis prices fell by an average 0.5 per cent.
[d?eil]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Children show “Paper-cutting Flowers” (China Southern Dance School under the China Dancers Association)
谎言4:太感谢了!我很喜欢!说谎原因:告诉别人他们送的礼物一团糟会让我看起来像是冷血的混蛋。
罗杰斯夫人还表示,正如条款中所述,她并没有同意她的儿子玩这个游戏。此外,由于这个游戏是免费的,所以该工作室不能够断言因为作弊软件而造成了利润损失。
吉尔伯特表示,对可穿戴设备的不断试验十分重要,但是现在短期内,人们还需要探讨一下:“技术的演进以及企业的研发力量共同推动了现有可穿戴产品的发展,但它们是否真的能够满足用户的需求;各公司又是否需要探索不同的合作模式,让可穿戴设备不仅限于早期使用者的圈子,而是被主流人群所接受”。
多名网友爆料称,周六日研究生入学考试开考前,部分试题和答案就已经提前被公布了。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

C罗巨无霸般的收入主要来源于两部分。一部分是他效力于西班牙豪门皇家马德里挣得的令人眼红的3850万英镑的年薪。另一部分来源于他为耐克、豪雅表和营养品公司康宝莱代言带来的总计2200万英镑的代言费。
《纽约时报》记者丹尼斯?格莱迪进入一间手术室,观察一项对24周、患有先天性脊椎裂的胎儿进行治疗的实验性技术。医生希望通过手术缓解患病婴儿的症状。他们目前已进行了28例手术,效果良好。报道中的胎儿母亲的预产期为1月14日。
'Increased production in the U.S. meant that spot prices weren't reacting quite as much as in previous geopolitical incidents,' Mr. Hansen said. There is so much supply that threats to it have less impact than previously, and 2014 will be 'the first year in a while when supply growth is going to outpace demand growth,' Mr. Hansen said.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

According to a notice jointly issued by the Ministry of Human Resources and Social Security and the Ministry of Finance, the average monthly payments for both enterprise and institution retirees will be increased by about 5.5% from the 2016 level.
Carry out deleveraging in an active and prudent way.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 北京西城将建2900套安置房
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The upshot is that Chinese trade looks to have been surprisingly strong last month. We expect exports to continue to perform well in the coming months on the back of strong global demand.
1. Bubble With No Name Yet triggers the biggest crash in 30 years
Whatever she needs to invoke the weightlessness of life in our new not-normal, she takes. "Is it the end of an era? Is it the end of America?" she intones in "When the World Was at War We Kept Dancing." "No, it's only the beginning."

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

通常冷静的分析师们早已习惯了汽车行业的缓慢增长,但是遇到特斯拉,他们就丢掉了一贯的谨慎。德意志银行(Deutsche Bank)的分析师罗德o拉切给该股设定了310美元的目标价格。无独有偶,摩根士丹利(Morgan Stanley)的分析师亚当o乔纳斯也将特斯拉的目标股价定为320美元,并称它是“世界上最重要的汽车公司”。
Days after her death, Ross’ mother, Alicia Jesquith, told reporters she needed answers for the sudden death of her daughter, described by friends and family as a vibrant, ambitious young girl who lit up the room.
在NBA,很少人能防得住罗斯。那么,你可以想象,在罗斯的高中年代,有着和现在一样的NBA身板,要防住他更是天方夜谭。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

一项由中国职业介绍机构智联招聘(Zhaopin)对1.15万名员工开展的调查发现,2016年底有50.9%的员工没有拿到年终奖。还有9.6%的员工则被告知年终奖会推迟至春节假期后发放。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

飓风厄玛在美国和全球的搜索排名图表中都位居前列,马特·劳拉成为在美国和世界搜索中人物搜索的第一名。这里是美国和全球排名前十的顺序表:

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

“我们现在从中国看到的情况不仅仅是巴西一国的现象,我们在整个拉美都看到了同样的情况,中国对所有市场的出口都在下降,”负责马士基航运在巴西、巴拉圭、乌拉圭和阿根廷业务的执行董事安东尼奥?多明格斯(Antonio Dominguez)表示,“已经连续几个季度出现这种情况,但随着我们进入(2016)年,这种局面变得越来越明显了。”
Despite the reported success of the Duke and Duchess of Cambridge's official visit to Canada back in September, timekeeping needs to be looked at for future trips.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 取消“公摊面积”行不行
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

足球赛艇皮划艇帆船
Age: 56
榜单前十位还包括:第五名的亚马逊总裁杰夫·贝佐斯,第六名的Facebook的马克·扎克伯格,位居第七的甲骨文公司老板拉里·埃里森,第八名的迈克尔·彭博及并列第九的科赫兄弟(大卫·科赫和迈克尔·科赫)。
1.Mitsubishi. Brand love: -12% / Rank: 360

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

BETTER CALL SAUL (AMC, Feb. 8) Vince Gilligan and Peter Gould’s “Breaking Bad” spinoff is probably the most anticipated new series of the winter. Starring Bob Odenkirk as the crooked lawyer Saul Goodman, the show is set before the action of “Breaking Bad,” so any appearances by Bryan Cranston or Aaron Paul would be cameos at best. But the audience favorite Jonathan Banks reprises his role as the phlegmatic enforcer Mike Ehrmantraut.
adj. 青春期的,青少年的

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

苹果(Apple)正面临着市值跳水的窘境,苹果股价从去年9月至今已下跌了35%。众多卖方分析师纷纷献计献策,现在甚至有人建议苹果推出廉价iPhone。摩根士丹利(Morgan Stanley)公司的凯蒂?休伯蒂对中国这一全球最大的智能手机市场进行了分析,并给大家算了一笔账。
根据新修订的中国刑法,在国家级别考试中,凡是组织、协助或是参与作弊行为的人,将会受到3至7年的有期徒刑。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

"When the actual dependency ratio of pension insurance gets down to three to one, the payment cannot be lower than 17 percent. If it drops to two to one ratio, it means that everyone is going to pay 25 percent. The financial burden gets heavier when the dependency ratio gets lower. The restructuring of pension system must be finalized in two years." Yang said.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

三月四日在好莱坞高地中心Mary J. Blige, Miguel, Gael García Bernal, Andra Day, Natalia LaFourcade, Keala Settle, Sufjan Stevens and Common将会演唱自己的原创歌曲来庆贺第90届奥斯卡。
李亦表示:“贫困阻碍了网民数量的进一步增加,使得网民数量占全部人口的比例只在50%左右。”
6.London's bike hire scheme couldn't be simpler, by the way: just go up to the terminal at any docking station, pay by card and take away one of our so-called "Boris bikes". When you're done with it, simply throw it into the nearest canal. They're disposable!
大型制药公司正在与美国癌症协会合作,以大幅折扣价为非洲患者提供抗癌药物。在整个非洲大陆,每年有45万人死于癌症,但其中有很多种癌症是可以治疗的,比如乳腺癌、宫颈癌和前列腺癌等。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

《经济学人智库》发布了2016年世界生活成本报告,根据各种产品和服务的成本对各国进行了排名。
[p?'spektiv]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

In China, there were still 43 million people in rural areas living in poverty at the end of 2016. The country aims to help all of them out of poverty by 2020.
"没人能阻止行动,我会用生命为代价一直投放宣传单张到北韩,"Park说,强调他一直有对抗北韩威胁的准备。
国际美容整形外科学会发布的数据显示,若考虑人口因素,韩国现在是全世界整形美容业最大的市场。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

清华大学在计算机科学和工程学两个学科中排名居首。这所中国院校今年取代了麻省理工学院,成为计算机科学最强学府。
This assumes, of course, that Apple can find a way to build a $330 iPhone with cheaper parts, a slower processor, a lower resolution screen and perhaps a plastic body, thatisn't, in the phrase Tim Cook used at a Goldman Sachs conference last week, "a crappy product."
It's hard enough for NBA defenders to stop Rose, so just imagine how ridiculously hard that must have been back in high school with Rose being nearly the same size that he is now.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Corkin died this year but shortly after, journalist Luke Dittrich published a book claiming Corkin buried inconvenient findings, shredded files, and acted unethically in gaining HM's consent.
中央纪委国际合作局局长腊翊凡表示:“在中共中央的领导下,我们将扩大与有关国家的司法合作,使腐败的外逃人员不存在“避罪天堂”。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The demagogue’s campaign leads naturally to despotism — the tyranny of the majority that is a mask on the tyranny of one.
haven
But now she's using her storybook looks for good, dressing up as the character to entertain children and cheer-up cancer patients.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Blake Griffin's high school appearance isn't that far off from how he looks today. Just add some hair and some size to his biceps, and you've got Blake Griffin today.
[?'pru:v?l]

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

女性地位继续上升。
I experienced this pessimism personally in Davos in January 2014. Several leading western intellectuals asked me whether war would break out between China and Japan. I was so confident that there would be no war in east Asia that I offered to take bets with ten-to-one odds against myself with eminent western journalists. Two took up my bets. And I will be collecting on these bets when I return to Davos in January.
stir

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

['t?]

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

The slower acceleration also tracks with trends in real estate investment, which felt a (slight) bite from property purchasing curbs in top-tier cities last month as nation-wide sales also decelerated in both volume and value terms.
这份榜单的四所英国大学分别是剑桥大学、牛津大学和伦敦大学和帝国理工学院。东京大学也位列前20名。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

在以结束迫害科索沃境内阿尔巴尼亚族为目的和平谈判破裂后,北约于1999年3月24日开始了轰炸行动。南斯拉夫和科索沃境内的目标均受到了打击,首先是对抗北约战机的塞尔维亚防空网络,接下来是一系列范围更大的目标,包括被指直接参与迫害科索沃人的南斯拉夫军事力量。目标清单中还包括南斯拉夫首都贝尔格莱德境内的政治和军事目标。
相比之下,小型货车销量却开始走下坡路,其成交量仅为7.13万台,同比跌幅31%。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

bene好+fic做+ial表形容词,“有…的”→有好处的
时间:2011-12-27 编辑:Jasmine

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

舞厅上面有一个可以旋转,发出五颜六色的光的球-ballroom
557,000 people were murdered across the world in 2001 alone. That number significantly dropped by 289,000 by 2008. The homocide rate is now in decline in 75% of nations.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

排名前50的IT富豪中,有五位是80后,其中包括滴滴出行现年33岁的首席执行官程维。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Local farmers must love this wireless company as much as its employees do. Once a week, San Diego-based Qualcomm hosts a farmers market at two of its locations. Items sold range from traditional produce to jams and jellies. Employees with CSA veggie box subscriptions can pick up their produce packages at one of the HQ's cafés.
根据FlightAware网站为福布斯编制的数据显示,总部位于落基山脉以西的航空公司在节假日期间的航班晚点率最低。
鉴于之前许多邦女郎在007电影中如昙花般一现,随后便星途黯淡,玛尔洛和经纪人正努力确保她与众多一流演员合作,正如邦德电影是用来为她的国际演艺生涯铺路一样。
共和党候选人时常表现出不确定以及偶尔会忘了自己要说的,好像在试图记住他的简要笔记。当奥巴马从一开始就咄咄逼人时他开始出汗,在伊朗、伊拉克、俄罗斯以及美国的军费开支的交流中他才表现得更好。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

自此之后,中国每年都会发布以12生肖属相为主题的农历新年纪念邮票。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

2017年度国家公务员考试上周日开考,大学生自主创业和"玉兔"月球车等最近的热门话题进入国考考题。
“It’s very easy to see the leaders in the current market are in a fairly tenuous or precarious position right now,” Gilbert says. “That’s evident by how quickly they’re innovating on each new device type.”
珍妮弗?劳伦斯曾于去年凭藉《乌云背后的幸福线》(Silver Linings Playbook)获得金球奖,而今年再度登台领奖的她表示,获奖感言还是让她倍感紧张。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

通过ETF购买计划,日本央行间接持有约22家日本大企业10%的股权,并持有整个日本股市的3%左右。一些人批评称,这是对日本股市“事实上的国有化”。
Probably the most awaited movie of all time and a big one for all Batman and Superman fans. We know that Batman is going to defeat Superman, but we don't know how he's going to do so in Dawn of Justice.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 西城三年腾退47处直管公房类文物
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

萨默塞特?毛姆(Somerset Maugham)曾形容法国里维埃拉(French Rivier)为“阴暗人物的阳光之地”。环视着酒店大堂里的“模特”,带着黑超的男人们似乎与他们相识,我似乎理解了毛姆。戛纳华丽的外表下有着其并不光彩的一面,就如湛蓝的海水下垃圾成堆。电影节开幕前,法国潜水员,同时也是环保人士的Laurent Lombard(劳伦?隆巴德)拍摄的戛纳河床沉积着大量垃圾废物的视频被疯传。我们被告知在此游泳并无危险。据《每日邮报》报道,市长已下令清理。但是小镇确实不再那么闪耀迷人了。
[k?n'vi:nj?nt]

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

墓地主人的身份依然是个迷。这座墓地曾经被盗过,而且墓地中没有任何的文字记录来表明这些死者的名字以及他们的职位。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

“在古代,库车的名字在中国文学中叫做龟兹,是建立在西域绿洲上的一个非常强大的城邦,研究人员写到。
While people in first-tier cities are under more pressure, smaller cities may not be the ideal place to live either, according to the 2016 Annual Report on Social Mentality of China by the Chinese Academy of Social Sciences.
补救办法:这种遗憾的棘手之处在于,它通常是后知后觉的。只有在你已经离开这个岗位并找到了更好的工作之后,你才会开始后悔为什么没有早点跳槽,即使这原本是不切实际的想法。你能做的就是找到使你留在这个岗位的理由,作为以后提醒自己的信号。另外,你还要通过各种途径使自己可以在机遇出现的时候能够快速抓住它,比如你可以按月或按季度重新审视自己并用新的成果来更新你的简历;同步更新在LinkedIn上的信息;准备应急资金以减轻你对当前工作的依赖;了解业内最新消息,以便知道自己可以在哪里大展拳脚。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

It was Somerset Maugham who said the French Riviera is “a sunny place for shady people” – and looking around at all the 'models' in the hotel lobbies and the men in dark sunglasses who seemed to know them, I knew what he meant. Behind the festival's shiny facade, there is an unseemly side – and beneath the azure waters, a polluted mess. The French diver and environmentalist Laurent Lombard's video of the Cannes seabed strewn with waste and debris went viral before the festival began. We were assured there was no danger to swimmers, and the mayor had it cleaned up according to the Daily Mail – but the Med had certainly lost some of its sparkle.
7.Yes, John was with me last night. – Because that’s what friends do… we agree and ask questions later。
韩云平称,去年质检总局组织了两次大规模的检查,涉及超过5300批的进口消费品,例如空气净化器、汽车刹车块、家用电器和服装等,其中超过1500批的商品不合格。
昨日发布的央行数据显示,中国外汇储备上月出现有记录以来第三大单月降幅。这重燃了人们对于中国遭遇资本外流的担忧,此前中国外汇储备似乎企稳。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

2016年全国硕士研究生招生考试周日结束后不久,教育部即接到考研试题泄露的举报。
In early December, authorities announced that market circuit breakers would be introduced become effective from January 1 in an effort to limit the volatility seen during the savage, summer sell-off from June. The circuit breakers would see trading in shares, options and futures halted for 15 minutes if they fell by more than 5 per cent. On their first day of use, that first threshold was breached just after the return from the lunchbreak, prompting a 15-minute halt.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

13. “Girlhood” (Céline Sciamma)
As a point of comparison, the combined 29.1 million total from those old master sales was 34 percent less than the 44.2 million Christie’s and Sotheby’s took in at equivalent events five years ago, in December 2011.
500富人榜中20%的富豪来自信息技术行业,而资产投资者正逐渐淡出该榜单。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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作为2014年资本计划的一部分内容,这家总部位于加州旧金山的银行表示将把股票回购量增加3.50亿股,总额达到近170亿美元。它还将派息提高约17%,达到了每股0.35美元。
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